(4-NH2) -Exatecan
(4-NH2) -Exatecan is a potent topoisomerase I inhibitor designed for the development of antibody-drug conjugates (ADCs) . It demonstrates significant antitumor activity in preclinical in vitro and in vivo models, making it a valuable payload for oncology research focused on targeted cancer therapies.
Product Specifications
CAS Number
2495742-21-5
Product Name Alternative
ADCCytotoxin, ADC Cytotoxin, (4 NH2) Exatecan, (4NH2) Exatecan, (4-NH-2) -Exatecan, (4-NH2) -Exatecan, Topo
Field of Research
Molecular Biology, Pharmacology & Drug Discovery
Purity
99.89% (May vary between batches)
Solubility
DMSO:80 mg/mL (198.3 mM)
Smiles
CC[C@@]1 (O) C (=O) OCc2c1cc1-c3nc4ccc (N) c5CCCc (c3Cn1c2=O) c45
Molecular Formula
C23H21N3O4
Molecular Weight
403.43
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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