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(Iso) -MS4322

(Iso) -MS4322 ((Iso) -YS43-22) is a potent and selective degrader of protein arginine methyltransferase 5 (PRMT5) . It effectively depletes PRMT5 protein levels in cellular models like MCF-7 cells and demonstrates broad antiproliferative activity against various cancer cell lines, supporting its investigation as a potential anticancer agent.

Product Specifications

CAS Number

2601727-80-2

Product Name Alternative

(Iso) -YS43-22, MS4322, MS-4322, MS4322 (isomer), MS 4322, HistoneMethyltransferase, Histone Methyltransferase, YS43-22 (isomer), PRMT5

Field of Research

Epigenetics & Chromatin, Pharmacology & Drug Discovery

Purity

98.85% (May vary between batches)

Solubility

DMSO:30 mg/mL (27.24 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (1.82 mM)

Smiles

C[C@@H] (NC (=O) [C@@H]1C[C@@H] (O) CN1C (=O) [C@H] (NC (=O) COCCOCCOCCOCCOCC (=O) N1CC (C1) Nc1cc (ncn1) C (=O) NC[C@H] (O) CN1CCc2ccccc2C1) C (C) (C) C) c1ccc (cc1) -c1scnc1C

Molecular Formula

C55H76N10O12S

Molecular Weight

1101.32

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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