VCP/p97 inhibitor-1
VCP/p97 inhibitor-1 is a potent small molecule targeting the AAA+ ATPase VCP/p97 with an IC50 of 54.7 nM. It disrupts protein homeostasis by inhibiting the degradation of ubiquitinated misfolded proteins via the proteasome. This compound is a valuable research tool for studying UPS-related pathologies, including cancer and neurodegenerative diseases, in cellular and animal models.
Product Specifications
CAS Number
2630950-38-6
Field of Research
Pharmacology & Drug Discovery; Cell Biology, Protein Biochemistry
Smiles
Cc1cc2c (NS (C) (=O) =O) cccc2n1-c1nc2CCCc2c (NCc2cccc (c2) B (O) O) n1
Molecular Formula
C24H26BN5O4S
Molecular Weight
491.37
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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