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KRAS G12C inhibitor 19

KRAS G12C inhibitor 19 is a potent and selective small molecule targeting the KRAS G12C mutation. It demonstrates robust anti-proliferative activity in vitro and has shown efficacy in inhibiting tumor growth in vivo, making it a valuable tool for oncology research focused on RAS-driven cancers.

Product Specifications

CAS Number

2649788-46-3

Product Name Alternative

KRAS G12C, KRAS G12C inhibitor 19, KRAS G-12C inhibitor 19

Field of Research

Pharmacology & Drug Discovery, Signal Transduction

Purity

97.46% (May vary between batches)

Solubility

DMSO:52.9 mg/mL (100.01 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:10 mg/mL (18.91 mM)

Smiles

C (#N) C=1C2=C (C=CC (F) =C2SC1N) C=3C (Cl) =C4C (=CC3F) C (=O) N5[C@@] (CCO4) (CN (C (C=C) =O) CC5) [H]

Molecular Formula

C25H19ClF2N4O3S

Molecular Weight

528.96

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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