PBRM1-BD2-IN-2
PBRM1-BD2-IN-2 is a selective, cell-active small molecule inhibitor targeting the second bromodomain (BD2) of PBRM1, with a Kd of 9.3 μM and an IC50 of 1.0 μM. It is a valuable chemical probe for investigating the role of PBRM1 in oncology research, supporting both in vitro and in vivo studies of chromatin remodeling in cancer contexts.
Product Specifications
CAS Number
2819989-57-4
Product Name Alternative
PBRM1BD2IN2, PBRM1-BD2-IN-2, EpigeneticReaderDomain, Epigenetic Reader Domain
Field of Research
Epigenetics & Chromatin
Purity
99.88% (May vary between batches)
Solubility
DMSO:45 mg/mL (144.63 mM)
Smiles
O=C1C=2C (NC (N1) C3=C (Cl) C=CC=C3F) =CC=CC2Cl
Molecular Formula
C14H9Cl2FN2O
Molecular Weight
311.14
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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