Agomelatine hydrochloride
Agomelatine hydrochloride is a potent and selective agonist of melatonin MT1 and MT2 receptors, with sub-nanomolar affinity. It also acts as a selective antagonist of the 5-HT2C receptor. This dual mechanism supports its research use in studying circadian rhythms, sleep disorders, and depression in both in vitro and in vivo models.
Product Specifications
CAS Number
1176316-99-6
Product Name Alternative
MT2 receptor, MT Receptor, MT1 receptor, MTReceptor, Agomelatine Hydrochloride, S 20098 Hydrochloride, S20098 Hydrochloride, S-20098 Hydrochloride, S-20098 hydrochloride
Field of Research
Metabolism Research, Neuroscience, Pharmacology & Drug Discovery
Purity
99.57% (May vary between batches)
Solubility
H2O:0.1 mg/mL (0.36 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (11.8 mM) ; DMSO:90 mg/mL (321.7 mM)
Smiles
Cl.COc1ccc2cccc (CCNC (C) =O) c2c1
Molecular Formula
C15H18ClNO2
Molecular Weight
279.76
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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