Guanoxabenz hydrochloride

Guanoxabenz hydrochloride is a selective α2 adrenergic receptor agonist, exhibiting a Ki of 4000 nM for the resting state and 40 nM for the active state of the α2A subtype. This small molecule is utilized in neuroscience and pharmacology research to study receptor activation mechanisms in both in vitro binding assays and in vivo models of sympathetic nervous system function.