B-Raf IN 8

B-Raf IN 8 (compound 7g) is a potent B-Raf inhibitor with an IC50 of 70.65 nM. It demonstrates in vitro antitumor activity against multiple cancer cell lines, including HEPG-2, HCT-116, MCF-7, and PC-3 cells, with IC50 values ranging from 9.78 to 29.85 μM, supporting its use in oncology research.