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NITD-916

NITD-916 is a potent, orally bioavailable 4-hydroxy-2-pyridone inhibitor targeting the Mycobacterium tuberculosis enoyl reductase InhA (IC50 = 570 nM) . It acts by forming a stable ternary complex with InhA and NADH, blocking substrate access and demonstrating antitubercular activity in both biochemical and whole-cell assays.

Product Specifications

CAS Number

1614262-83-7

Product Name Alternative

NITD916, NITD-916, NITD 916, tuberculosis

Field of Research

Infectious Disease & Virology

Purity

98.98% (May vary between batches)

Solubility

DMSO:15 mg/mL (48.17 mM)

Smiles

OC1=C (C2=CC=CC=C2) C (=O) NC (CC3CCC (C) (C) CC3) =C1

Molecular Formula

C20H25NO2

Molecular Weight

311.42

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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