NITD-916
NITD-916 is a potent, orally bioavailable 4-hydroxy-2-pyridone inhibitor targeting the Mycobacterium tuberculosis enoyl reductase InhA (IC50 = 570 nM) . It acts by forming a stable ternary complex with InhA and NADH, blocking substrate access and demonstrating antitubercular activity in both biochemical and whole-cell assays.
Product Specifications
CAS Number
1614262-83-7
Product Name Alternative
NITD916, NITD-916, NITD 916, tuberculosis
Field of Research
Infectious Disease & Virology
Purity
98.98% (May vary between batches)
Solubility
DMSO:15 mg/mL (48.17 mM)
Smiles
OC1=C (C2=CC=CC=C2) C (=O) NC (CC3CCC (C) (C) CC3) =C1
Molecular Formula
C20H25NO2
Molecular Weight
311.42
Storage Conditions
-20°C
Notes
For research use only.
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