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NLRP3-IN-10

NLRP3-IN-10 (ZVN26391) is a potent small molecule inhibitor of the NLRP3 inflammasome, suppressing IL-1β release (IC50 = 251.1 nM) and attenuating ASC speck formation. It is a valuable research tool for investigating NLRP3-driven pathologies, including inflammatory and autoimmune diseases, in both cellular and animal models.

Product Specifications

CAS Number

2641826-39-1

Product Name Alternative

ZVN 26391, ZVN26391, ZVN-26391, NLRP3, NLRP3-IN-10

Field of Research

Cell Biology, Immunology & Inflammation, Signal Transduction

Purity

99.06% (May vary between batches)

Solubility

DMSO:4.4 mg/mL (12.05 mM)

Smiles

COc1cc (\C=C\C (=O) c2ccc (F) cc2) c (OC) cc1Br

Molecular Formula

C17H14BrFO3

Molecular Weight

365.19

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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