NLRP3-IN-10
NLRP3-IN-10 (ZVN26391) is a potent small molecule inhibitor of the NLRP3 inflammasome, suppressing IL-1β release (IC50 = 251.1 nM) and attenuating ASC speck formation. It is a valuable research tool for investigating NLRP3-driven pathologies, including inflammatory and autoimmune diseases, in both cellular and animal models.
Product Specifications
CAS Number
2641826-39-1
Product Name Alternative
ZVN 26391, ZVN26391, ZVN-26391, NLRP3, NLRP3-IN-10
Field of Research
Cell Biology, Immunology & Inflammation, Signal Transduction
Purity
99.06% (May vary between batches)
Solubility
DMSO:4.4 mg/mL (12.05 mM)
Smiles
COc1cc (\C=C\C (=O) c2ccc (F) cc2) c (OC) cc1Br
Molecular Formula
C17H14BrFO3
Molecular Weight
365.19
Storage Conditions
-20°C
Notes
For research use only.
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