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XT2

XT2 is a potent and selective oral NIK inhibitor (IC50 = 9.1 nM) . It demonstrates efficacy in acute liver injury models by reducing ALT levels and immune cell infiltration, highlighting its utility for research in liver inflammation and NF-κB pathway biology.

Product Specifications

CAS Number

2582816-37-1

Field of Research

Signal Transduction

Smiles

C[C@@] (O) (C#Cc1ccc (F) c (c1) -c1c[nH]c2cnc (N) nc12) c1nccs1

Molecular Formula

C19H14FN5OS

Molecular Weight

379.41

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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