GAK inhibitor 2
GAK inhibitor 2 (Compound 14g) is a potent and selective cyclin G-associated kinase (GAK) inhibitor (IC50 = 24 nM) . It demonstrates significant antiviral activity against dengue virus (DENV) in vitro (EC50 = 1.049 μM), making it a valuable chemical probe for researching host-directed antiviral strategies and GAK biology.
Product Specifications
CAS Number
2396706-31-1
Field of Research
Infectious Disease & Virology, Pharmacology & Drug Discovery
Smiles
C[C@@H]1CN (C2=C3C (=NS2) C=CC (=N3) C4=CC (OC) =C (OC) C=C4) C[C@H] (C) O1
Molecular Formula
C20H23N3O3S
Molecular Weight
385.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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