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Tovinontrine

Tovinontrine (IMR-687) is a highly selective phosphodiesterase-9 (PDE9) inhibitor with reported IC50 values of 8.19 nM and 9.99 nM for PDE9A1 and PDE9A2, respectively. It is a research compound investigated for sickle cell disease, with studies exploring its effects on fetal hemoglobin induction in both cellular and animal models.

Product Specifications

CAS Number

2062661-53-2

Product Name Alternative

PDE9A, IMR 687, IMR687, IMR-687, Tovinontrine

Field of Research

Metabolism Research

Purity

98.14% (May vary between batches)

Solubility

DMSO:90 mg/mL (228.15 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (8.37 mM)

Smiles

C[C@@H]1CN (Cc2ncccn2) C[C@H]1c1cn2c (ncc2c (=O) [nH]1) C1CCOCC1

Molecular Formula

C21H26N6O2

Molecular Weight

394.47

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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