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RKI-1447 dihydrochloride

RKI 1447 dihydrochloride is a potent and selective ROCK inhibitor with IC50 values of 14.5 nM for ROCK1 and 6.2 nM for ROCK2. It has been shown in research to suppress colorectal cancer cell proliferation and induce apoptosis in vitro, supporting its investigation in oncology and cell signaling studies.

Product Specifications

CAS Number

1782109-09-4

Field of Research

Cell Biology, Signal Transduction, Stem Cell & Developmental Biology

Smiles

Cl.Cl.Oc1cccc (CNC (=O) Nc2nc (cs2) -c2ccncc2) c1

Molecular Formula

C16H16Cl2N4O2S

Molecular Weight

399.29

Storage Conditions

-20°C

Notes

For research use only.

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