RKI-1447 dihydrochloride
RKI 1447 dihydrochloride is a potent and selective ROCK inhibitor with IC50 values of 14.5 nM for ROCK1 and 6.2 nM for ROCK2. It has been shown in research to suppress colorectal cancer cell proliferation and induce apoptosis in vitro, supporting its investigation in oncology and cell signaling studies.
Product Specifications
CAS Number
1782109-09-4
Field of Research
Cell Biology, Signal Transduction, Stem Cell & Developmental Biology
Smiles
Cl.Cl.Oc1cccc (CNC (=O) Nc2nc (cs2) -c2ccncc2) c1
Molecular Formula
C16H16Cl2N4O2S
Molecular Weight
399.29
Storage Conditions
-20°C
Notes
For research use only.
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