PD-1/PD-L1-IN-14
PD-1/PD-L1-IN-14 (compound 17) is a small molecule inhibitor that blocks PD-1/PD-L1 binding with an IC50 of 27.8 nM, leading to PD-L1 dimerization, internalization, and degradation. It is used in cancer immunotherapy research, including in vitro cellular assays and in vivo animal models for studying antitumor immune responses.
Product Specifications
CAS Number
2499965-12-5
Field of Research
Cancer Biology; Immunology & Inflammation, Cell Biology, Immunology & Inflammation
Smiles
CC1=C (C=2OC (NC3=CC (CNCCO) =CC=C3) =NN2) C=CC=C1C4=CC=CC=C4
Molecular Formula
C24H24N4O2
Molecular Weight
400.47
Storage Conditions
-20°C
Notes
For research use only.
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