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SIRT5 inhibitor 2

SIRT5 inhibitor 2 (compound 49) is a potent and selective inhibitor of SIRT5 deacetylase activity with an IC50 of 2.3 μM. This tool compound enables the investigation of SIRT5's role in metabolic reprogramming and cellular stress responses, supporting research in oncology and neurodegenerative disease models both in vitro and in vivo.

Product Specifications

CAS Number

340306-87-8

Field of Research

Epigenetics & Chromatin, Molecular Biology, Pharmacology & Drug Discovery

Purity

99.38% (May vary between batches)

Smiles

O=C1NC (=S) N (C (=O) C1=CC=2OC (=CC2) C=3C=CC=C (Cl) C3Cl) CC=C

Molecular Formula

C18H12Cl2N2O3S

Molecular Weight

407.27

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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