EGFR-IN-49
EGFR-IN-49 is a selective small molecule inhibitor targeting EGFR T790M and T790M/L858R mutants with IC50 values of 65.0 nM and 13.6 nM, respectively. It induces dose-dependent apoptosis and is a useful tool compound for in vitro and in vivo studies of non-small cell lung cancer resistance mechanisms.
Product Specifications
CAS Number
2459932-81-9
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
O (C1=C2C (=NC (NC3=CC (C#N) =CC=C3) =N1) C=CS2) C4=CC (NC (C=C) =O) =CC=C4
Molecular Formula
C22H15N5O2S
Molecular Weight
413.45
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog