AMG9678
AMG9678 is a potent and selective orally bioavailable antagonist of the TRPM8 ion channel, exhibiting an IC50 of 31.2 nM. This compound is a valuable research tool for investigating TRPM8's role in vivo and in vitro in areas such as cold sensation, migraine, and overactive bladder.
Product Specifications
CAS Number
1159997-27-9
Field of Research
Pharmacology & Drug Discovery
Smiles
C (N[C@H] (C (F) (F) F) C) (=O) N1[C@@H] (C=2C (CC1) =CC=CC2) C3=CC=C (C (F) (F) F) C=C3
Molecular Formula
C20H18F6N2O
Molecular Weight
416.36
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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