HDAC8/BRPF1-IN-1
HDAC8/BRPF1-IN-1 (Compound 23a) is a dual inhibitor targeting human HDAC8 (IC50: 443 nM) and BRPF1 (Kd: 67 nM) with selectivity over HDAC1 and HDAC6. This compound serves as a chemical probe for epigenetic research, enabling the study of histone acetylation mechanisms in cancer and neurodevelopmental disease models.
Product Specifications
CAS Number
2484255-85-6
Field of Research
Epigenetics & Chromatin, Molecular Biology
Smiles
CN1C=2C (=CC (NS (=O) (=O) C3=C (OC) C=CC (C (NO) =O) =C3) =CC2) C=C (C) C1=O
Molecular Formula
C19H19N3O6S
Molecular Weight
417.44
Storage Conditions
-20°C
Notes
For research use only.
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