NRX-2663
NRX-2663 is a small molecule that potently enhances the interaction between β-catenin and the SCFβ-TrCP E3 ubiquitin ligase complex, with a reported Kd of 54.8 nM and an EC50 of 22.9 nM. This compound is a valuable research tool for studying Wnt/β-catenin signaling, protein degradation mechanisms, and has utility in both in vitro biochemical assays and cellular models of oncogenesis.
Product Specifications
CAS Number
2763260-34-8
Field of Research
Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology
Smiles
O (C1=C (C (NC2=CC (C (O) =O) =CC=C2) =O) C (=O) NC (C (F) (F) F) =C1) C3=CC=CC=C3
Molecular Formula
C20H13F3N2O5
Molecular Weight
418.32
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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