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MRL-871

MRL-871 is a selective allosteric inhibitor of RORγt, reducing IL-17a mRNA in EL4 cells, and also acts as a partial PPARγ agonist. This small molecule is a valuable research tool for investigating Th17 cell biology and autoimmune disease mechanisms in both cellular and animal models.

Product Specifications

CAS Number

1392809-08-3

Product Name Alternative

MRL871

Field of Research

Metabolism Research

Purity

99.66% (May vary between batches)

Solubility

DMSO:15 mg/mL (33.72 mM)

Smiles

O=C (O) C=1C=CC (=CC1) C2=NN (C (=O) C=3C (Cl) =CC=CC3C (F) (F) F) C=4C=CC=CC24

Molecular Formula

C22H12ClF3N2O3

Molecular Weight

444.79

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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