(R) -MLT-985
(R) -MLT-985 is a potent and selective MALT1 protease inhibitor with an IC50 of 3 nM. It effectively blocks MALT1-dependent IL-2 production in Jurkat cells (IC50: 20 nM) and suppresses pathogenic CARD11/BCL10/MALT1 signaling and growth in ABC-DLBCL cell models, making it a valuable research tool for studying lymphomas and immune signaling pathways.
Product Specifications
CAS Number
1832577-07-7
Field of Research
Immunology & Inflammation
Smiles
[C@@H] (OC) (C) C=1N2C (N=CC1NC (NC=3C=C (Cl) C (=NC3) N4N=CC=N4) =O) =CC (Cl) =N2
Molecular Formula
C17H15Cl2N9O2
Molecular Weight
448.27
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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