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IRAK4-IN-20

IRAK4-IN-20 is a potent, orally bioavailable IRAK4 inhibitor with an IC50 of 3.55 nM. It demonstrates anti-inflammatory and anticancer activities in research, supporting its investigation in models of diseases like ARDS, cancer, and autoimmune disorders through both in vitro and in vivo studies.

Product Specifications

CAS Number

1931994-80-7

Product Name Alternative

BAY 1834845, BAY1834845, BAY-1834845, IRAK4, IRAK4-IN-20

Field of Research

Immunology & Inflammation, Signal Transduction

Purity

97.32% (May vary between batches)

Solubility

DMSO:25 mg/mL (55.5 mM)

Smiles

C (C) (C) (O) C1=CC=2C (C=C1NC (=O) C=3N=C (C (F) (F) F) C=CC3) =CN (CCC (C) (C) O) N2

Molecular Formula

C22H25F3N4O3

Molecular Weight

450.45

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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