TREM2 agonist-2
TREM2 agonist-2 (I-192) is a potent, orally bioavailable small molecule activator of Triggering Receptor Expressed on Myeloid cells 2. It is a valuable research tool for investigating TREM2 pathway biology in models of neurodegenerative diseases, including Alzheimer's disease, in both cellular and animal studies.
Product Specifications
CAS Number
2738485-98-6
Product Name Alternative
TREM2
Field of Research
Neuroscience; Pharmacology & Drug Discovery
Purity
98.72% (May vary between batches)
Solubility
DMSO:257.5 mg/mL (569.79 mM)
Smiles
CC1=NC=2C (=NC (=CC2N=C1C) [C@@H]3C[C@@H] (OCC3) C4=CN (C) N=C4) C5=C (F) C=C (Cl) C=C5
Molecular Formula
C24H23ClFN5O
Molecular Weight
451.92
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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