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TREM2 agonist-2

TREM2 agonist-2 (I-192) is a potent, orally bioavailable small molecule activator of Triggering Receptor Expressed on Myeloid cells 2. It is a valuable research tool for investigating TREM2 pathway biology in models of neurodegenerative diseases, including Alzheimer's disease, in both cellular and animal studies.

Product Specifications

CAS Number

2738485-98-6

Product Name Alternative

TREM2

Field of Research

Neuroscience; Pharmacology & Drug Discovery

Purity

98.72% (May vary between batches)

Solubility

DMSO:257.5 mg/mL (569.79 mM)

Smiles

CC1=NC=2C (=NC (=CC2N=C1C) [C@@H]3C[C@@H] (OCC3) C4=CN (C) N=C4) C5=C (F) C=C (Cl) C=C5

Molecular Formula

C24H23ClFN5O

Molecular Weight

451.92

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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