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GSK2945 hydrochloride

GSK2945 hydrochloride is a potent and selective Rev-erbα/REV-ERBα antagonist with EC50 values of approximately 21 μM. It is utilized in circadian rhythm and metabolic research, where it has been shown in vitro to upregulate cholesterol 7α-hydroxylase, a key enzyme in bile acid synthesis.

Product Specifications

Field of Research

Metabolism Research

Molecular Formula

C20H19Cl3N2O2S

Molecular Weight

457.8

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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