GSK2945 hydrochloride
GSK2945 hydrochloride is a potent and selective Rev-erbα/REV-ERBα antagonist with EC50 values of approximately 21 μM. It is utilized in circadian rhythm and metabolic research, where it has been shown in vitro to upregulate cholesterol 7α-hydroxylase, a key enzyme in bile acid synthesis.
Product Specifications
Field of Research
Metabolism Research
Molecular Formula
C20H19Cl3N2O2S
Molecular Weight
457.8
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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