MIR002
MIR002 is an orally bioavailable small molecule that dually inhibits POLA1 and HDAC11, demonstrating potent in vivo antitumor efficacy. Its mechanism involves inducing p53 acetylation and p21 expression, leading to G1/S cell cycle arrest and apoptosis in cancer cells, making it a valuable tool for oncology and epigenetics research.
Product Specifications
CAS Number
2217671-64-0
Field of Research
Cell Biology, Epigenetics & Chromatin, Molecular Biology
Smiles
O (CC (NO) =O) C1=C (C23CC4CC (C2) CC (C3) C4) C=C (C=C1) C5=CC=C (/C=C/C (O) =O) C=C5
Molecular Formula
C27H29NO5
Molecular Weight
447.52
Storage Conditions
-20°C
Notes
For research use only.
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