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PPARα/δ agonist 1

This potent and selective PPARα/δ dual agonist (EC50: 7.0 nM PPARα, 8.4 nM PPARδ; >150-fold selectivity over PPARγ) is a valuable research tool for investigating metabolic diseases. It is applicable in both in vitro assays and in vivo models, particularly for studies related to non-alcoholic steatohepatitis (NASH) .

Product Specifications

CAS Number

2760128-48-9

Field of Research

Metabolism Research, Molecular Biology, Pharmacology & Drug Discovery

Smiles

O=C1N (C=NN1CC2=CC (C) =C (OC (C (O) =O) (C) C) C (C) =C2) C3=CC=C (OC (F) (F) F) C=C3

Molecular Formula

C22H22F3N3O5

Molecular Weight

465.42

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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FLIP-L (FLICE-like Inhibitory Protein Long Form, CFLAR, CASH, CASP8AP1, CLARP, MRIT, CASP8 and FADD-like Apoptosis Regulator, Caspase Homolog, CASH, Caspase-eight-related Protein, Casper, Caspase-like Apoptosis Regulatory Protein, CLARP, Cellular FLICE-like Inhibitory Protein, c-FLIP, FADD-like Antiapoptotic Molecule 1, FLAME-1, Inhibitor of FLICE, MACH-related Inducer of Toxicity, Usurpin) discontinued. See F4550-01
F4550-70H 100 µg

FLIP-L (FLICE-like Inhibitory Protein Long Form, CFLAR, CASH, CASP8AP1, CLARP, MRIT, CASP8 and FADD-like Apoptosis Regulator, Caspase Homolog, CASH, Caspase-eight-related Protein, Casper, Caspase-like Apoptosis Regulatory Protein, CLARP, Cellular FLICE-like Inhibitory Protein, c-FLIP, FADD-like Antiapoptotic Molecule 1, FLAME-1, Inhibitor of FLICE, MACH-related Inducer of Toxicity, Usurpin) discontinued. See F4550-01

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