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OTS447

OTS447 is a potent and selective FLT3 tyrosine kinase inhibitor with an IC50 of 21 nM. It is a valuable research tool for investigating acute myeloid leukemia (AML), demonstrating activity in both cellular assays and in vivo xenograft models.

Product Specifications

CAS Number

1356943-67-3

Product Name Alternative

OTS-447, OTS 447, FLT3

Field of Research

Cardiovascular Research, Signal Transduction

Purity

97.72% (May vary between batches)

Solubility

DMSO:2.33 mg/mL (5 mM)

Smiles

CCN (CC) C1CCC (CC1) Nc1c (cnc2ccc (cc12) -c1ccc (O) c (Cl) c1) C (C) =O

Molecular Formula

C27H32ClN3O2

Molecular Weight

466.02

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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