FLT3/CDK4-IN-1
FLT3/CDK4-IN-1 is a potent and selective oral dual inhibitor of FLT3 (IC50=7 nM) and CDK4 (IC50=11 nM) . It demonstrates anti-proliferative activity in cellular assays and exhibits in vivo antitumor efficacy, supporting its use in oncology research, particularly for studying FLT3-ITD mutant AML and CDK4/6-driven cancers.
Product Specifications
CAS Number
2762296-44-4
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
C (C) (C) N1C=2C (=NC=C (C2) C3=NC (NC4=CC (F) =C (C=C4) N5CCN (CC) CC5) =NC=C3F) C=N1
Molecular Formula
C25H28F2N8
Molecular Weight
478.54
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
