Aβ-IN-1
Aβ-IN-1 is a potent, orally bioavailable γ-secretase modulator that selectively lowers Aβ42 levels (IC50 = 0.091 μM) in cellular assays without inhibiting CYP3A4. Its sustained pharmacokinetic profile supports its utility in researching Alzheimer's disease pathogenesis and therapy in both in vitro and in vivo models.
Product Specifications
CAS Number
2766509-32-2
Product Name Alternative
Gammasecretase, γ secretase (Aβ42)
Field of Research
Neuroscience, Protein Biochemistry, Stem Cell & Developmental Biology
Purity
99.10% (May vary between batches)
Solubility
H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:< 1 mg/mL (insoluble or slightly soluble)
Smiles
C[C@@]12[C@@]3 ([C@] ([C@]4 ([C@] (C) (CC3) [C@@] ([C@@H] (CCCC (C) C) C) (CC4) [H]) [H]) (CC=C1C=5C (CC2) =NC=6C (C5C) =CC=CC6) [H]) [H]
Molecular Formula
C35H49N
Molecular Weight
483.77
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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