BRD4 Inhibitor-18
BRD4 Inhibitor-18 is a potent small molecule (IC50 = 110 nM) featuring a hydrophobic acetylcyclopentane moiety. It effectively suppresses proliferation in BRD4-high leukemia cells like MV-4-11 by inducing cell cycle arrest in G0/G1 phase and promoting apoptosis, making it a valuable tool for epigenetic and cancer research.
Product Specifications
CAS Number
2451219-73-9
Field of Research
Cell Biology, Epigenetics & Chromatin, Epigenetics & Chromatin; Pharmacology & Drug Discovery
Smiles
CN1C=2C=3C (C (=NC (CC (NC4CCCC4) =O) C2SC1=O) C5=CC=C (Cl) C=C5) =CC (OC) =CC3
Molecular Formula
C26H26ClN3O3S
Molecular Weight
496.02
Storage Conditions
-20°C
Notes
For research use only.
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