Ki16198
Ki16198 is an orally bioavailable methyl ester derivative of Ki16425 that acts as a selective LPA1 and LPA3 receptor antagonist, with respective Ki values of 0.34 μM and 0.93 μM. It is utilized in research models, including in vitro signaling assays and in vivo studies investigating pancreatic cancer progression and metastatic spread.
Product Specifications
CAS Number
355025-13-7
Product Name Alternative
BxPC-3, Lysophospholipid Receptor, inhibit, Ki16198, Ki 16198, Ki-16198, Inhibitor, lung, liver metastasis, LPL, LPLReceptor, LPL Receptor, LPAReceptor, LPA3, LPA1, LPA Receptor
Field of Research
Pharmacology & Drug Discovery
Purity
97.60% (May vary between batches)
Solubility
DMSO:50 mg/mL (102.25 mM) ;10% DMSO+90% Corn Oil:2.5 mg/mL (5.11 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:33 mg/mL (67.49 mM)
Smiles
COC (=O) CCSCc1ccc (cc1) -c1onc (C) c1NC (=O) OC (C) c1ccccc1Cl
Molecular Formula
C24H25ClN2O5S
Molecular Weight
488.98
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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