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JAK-IN-20

JAK-IN-20 is a potent, orally bioavailable pan-JAK inhibitor targeting JAK1, JAK2, and JAK3 with IC50 values of 7, 5, and 14 nM, respectively. It exhibits excellent pharmacokinetics and anti-inflammatory activity in vivo, making it suitable for research in autoimmune diseases, inflammation models, and hematological malignancies as per published studies.

Product Specifications

CAS Number

1654776-91-6

Field of Research

Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

Smiles

FC=1C (=NC (NC2=CC=C (C=C2) N3CCC (CC3) N4CCOCC4) =NC1) C5=CC=C (C (NCC#N) =O) C=C5

Molecular Formula

C28H30FN7O2

Molecular Weight

515.58

Storage Conditions

-20°C

Notes

For research use only.

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