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PDGFRα/FLT3-ITD-IN-2

PDGFRα/FLT3-ITD-IN-2 is a potent small molecule inhibitor with high selectivity for FLT3 (IC50: 4 nM) over PDGFRα. It is a valuable research tool for investigating FLT3-ITD-driven acute myeloid leukemia, with studies demonstrating its activity in both cellular assays and in vivo xenograft models.

Product Specifications

CAS Number

2761259-09-8

Field of Research

Cardiovascular Research, Cell Biology, Signal Transduction

Smiles

N (CC1=CC=C (C (NCCCCN) =O) C=C1) C2=C3C (N (C=N3) C4CCCC4) =NC (N[C@@H]5CC[C@@H] (N) CC5) =N2

Molecular Formula

C28H41N9O

Molecular Weight

519.68

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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