PDGFRα/FLT3-ITD-IN-2
PDGFRα/FLT3-ITD-IN-2 is a potent small molecule inhibitor with high selectivity for FLT3 (IC50: 4 nM) over PDGFRα. It is a valuable research tool for investigating FLT3-ITD-driven acute myeloid leukemia, with studies demonstrating its activity in both cellular assays and in vivo xenograft models.
Product Specifications
CAS Number
2761259-09-8
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
N (CC1=CC=C (C (NCCCCN) =O) C=C1) C2=C3C (N (C=N3) C4CCCC4) =NC (N[C@@H]5CC[C@@H] (N) CC5) =N2
Molecular Formula
C28H41N9O
Molecular Weight
519.68
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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