SOS1-IN-5
SOS1-IN-5 is a potent, pyrimidine-based bicyclic SOS1 inhibitor that disrupts the KRAS-SOS1 interaction to block KRAS activation. This compound demonstrates broad-spectrum anti-KRAS activity and is a valuable chemical probe for oncology research, applicable in both cellular and biochemical assays to study RAS pathway signaling.
Product Specifications
CAS Number
2716956-47-5
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Smiles
N ([C@H] (C) C1=CC (C (F) (F) F) =CC (N) =C1) C=2C3=C (C=C4C (=C3) OCCOCCOCCOCCO4) N=C (C) N2
Molecular Formula
C26H31F3N4O5
Molecular Weight
536.54
Storage Conditions
-20°C
Notes
For research use only.
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