KRAS G12C inhibitor 43
This small molecule is a potent and selective KRAS G12C inhibitor, demonstrating sub-micromolar IC50 values against H358 cell proliferation and migration. It serves as a valuable research tool for investigating KRAS-driven oncogenesis in both in vitro and in vivo models, supporting studies in cancer biology and targeted therapy development.
Product Specifications
CAS Number
2648808-69-7
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Smiles
O (C[C@H]1N (C) CCC1) C=2N=C (C3=C (N=C (C=C3) C=4C5=C (C=C (OC) C4) C=CC=C5) N2) N6C[C@H] (CC#N) N (C (C=C) =O) CC6
Molecular Formula
C33H35N7O3
Molecular Weight
577.68
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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