NXPZ-2
NXPZ-2 is a potent, orally bioavailable small molecule inhibitor of the Keap1-Nrf2 protein-protein interaction (Ki: 95 nM) . It demonstrates efficacy in Alzheimer's disease mouse models, reducing Aβ-induced cognitive deficits and neuropathology, making it a valuable research tool for studying Nrf2 pathway modulation in neurodegenerative disorders.
Product Specifications
CAS Number
2254492-08-3
Field of Research
Immunology & Inflammation
Smiles
N (S (=O) (=O) C1=CC=C (OC) C=C1) (CC (N) =O) C=2C3=C (C (N (S (=O) (=O) C4=CC=C (N) C=C4) CC (N) =O) =CC2) C=CC=C3
Molecular Formula
C27H27N5O7S2
Molecular Weight
597.66
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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