JAK2 JH2 binder-1
JAK2 JH2 binder-1 is a potent and selective inhibitor targeting the JAK2 pseudokinase domain (JH2) with a Ki of 37.1 nM. This compound serves as a valuable research tool for investigating the pathophysiology of myeloproliferative neoplasms in both cellular and animal model systems.
Product Specifications
CAS Number
2923309-41-3
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Smiles
O=C (O) C1=CC (=CC=C1OCC=2C=CC=CC2) C=3C=CC (=CC3) NC (=O) N4N=C (N=C4N) NC5=CC=C (C=C5) S (=O) (=O) N
Molecular Formula
C29H25N7O6S
Molecular Weight
599.62
Storage Conditions
-20°C
Notes
For research use only.
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