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PRI-724

PRI-724 is a selective small molecule that disrupts the β-catenin/CBP protein-protein interaction. It is used in cancer research, particularly for studying Wnt/β-catenin signaling pathways, and has been investigated in both in vitro assays and in vivo preclinical models.

Product Specifications

CAS Number

1422253-38-0

Product Name Alternative

Beta-catenin, betacatenin, bcatenin, C-82 prodrug, Foscenvivint, ICG-001 analog, Wnt/betacatenin, Wnt/b-catenin, Wnt, PRI 724, PRI724, PRI-724, Wnt/β-catenin, βcatenin

Field of Research

Signal Transduction, Stem Cell & Developmental Biology

Purity

98.25% (May vary between batches)

Solubility

DMSO:55 mg/mL (83.51 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.04 mM) ; Ethanol:1.8 mg/mL (2.73 mM)

Smiles

C ([C@@H]1N2[C@@] (N (C (NCC3=CC=CC=C3) =O) N (C) CC2=O) ([C@H] (C) N (CC=4C5=C (C=CC4) C=CC=N5) C1=O) [H]) C6=CC=C (OP (=O) (O) O) C=C6

Molecular Formula

C33H35N6O7P

Molecular Weight

658.64

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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