NSC697923
NSC-697923 is a UBE2N (Ubc13) inhibitor that induces neuroblastoma cell death via p53 nuclear import in wild-type cells or JNK-mediated apoptosis in p53-mutant cells. It also suppresses DNA damage and NF-κB signaling, demonstrating antitumor activity in vitro. This compound is a useful research tool for studying ubiquitination, apoptosis pathways, and neuroblastoma models.
Product Specifications
CAS Number
343351-67-7
Product Name Alternative
Ubc13, NSC697923, NSC-697923, NSC 697923, 2-[ (4-methylphenyl) sulfonyl]-5-nitrofuran, E3Enzyme, E3 Enzyme, E2Enzyme, E2 Enzyme, E1 Enzyme, E1Enzyme
Field of Research
Cell Biology, Protein Biochemistry
Purity
>98%
Bioactivity
Ubiquitin E2 ligase inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 5 mg/ml with warming)
Smiles
Cc1ccc (cc1) S (=O) (=O) c1ccc (o1) [N+] ([O-]) =O
Molecular Formula
C11H9NO5S
Molecular Weight
267.26
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
2-[ (Methylphenyl) sulfonyl]-5-nitrofuran
Available Sizes
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