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R1487 Hydrochloride

R1487 Hydrochloride is a potent, selective, and orally bioavailable p38α MAPK inhibitor. It is utilized in metabolic disease research, enabling the investigation of inflammatory signaling pathways in both cellular assays and animal models.

Product Specifications

CAS Number

449808-64-4

Product Name Alternative

Autophagy, IL-1β, TNFα, R1487 (Hydrochloride), R1487 Hydrochloride, R1487, R-1487, R-1487 Hydrochloride, THP-1, R 1487, R 1487 Hydrochloride, p38MAPK, p38α, p38 MAPK

Field of Research

Cell Biology, Signal Transduction

Purity

99.35% (May vary between batches)

Solubility

H2O:< 1 mg/mL (insoluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.71 mM) ; DMSO:16 mg/mL (37.66 mM)

Smiles

Cl.O=C1C (OC2=CC=C (F) C=C2F) =CC=3C=NC (=NC3N1C) NC4CCOCC4

Molecular Formula

C19H19ClF2N4O3

Molecular Weight

424.83

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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