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AS601245.2TFA (345987-15-7 free base)

AS601245.2TFA (345987-15-7 free base) is a potent, cell-permeable inhibitor of JNK isoforms, with IC50 values of 150 nM (hJNK1), 220 nM (hJNK2), and 70 nM (hJNK3) . This compound is widely used in research to investigate JNK signaling pathways in cellular models of apoptosis, inflammation, and neurological disorders.

Product Specifications

CAS Number

345987-16-8

Product Name Alternative

JNK, AS601245.2TFA, AS601245.2TFA (345987 15 7 free base), AS601245.2TFA (345987157 free base), AS-601245.2TFA (345987-15-7 free base), 345987-15-7, 345987-15-7 free base

Field of Research

Signal Transduction

Solubility

DMSO:60 mg/mL (99.92 mM)

Smiles

OC (=O) C (F) (F) F.OC (=O) C (F) (F) F.N#CC (c1nc2ccccc2s1) c1ccnc (NCCc2cccnc2) n1

Molecular Formula

C24H18F6N6O4S

Molecular Weight

600.50

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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