Z-Gly-Pro-Arg-AMC (hydrochloride)

Z-Gly-Pro-Arg-AMC hydrochloride a fluorescent trypsin and cathepsin K substrate. Z-Gly-Pro-Arg-AMC hydrochloride can be used to determine trypsin and cathepsin K activity[1][2].

Product Specifications

CAS Number

[201928-42-9]

UNSPSC

12352209

Hazard Statement

H302, H315, H319

Target

Cathepsin

Type

Peptides

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/z-gly-pro-arg-amc-hydrochloride.html

Purity

98.63

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC(C1=CC=C(NC([C@H](CCCNC(N)=N)NC([C@H]2N(CCC2)C(CNC(OCC3=CC=CC=C3)=O)=O)=O)=O)C=C1O4)=CC4=O.Cl

Molecular Formula

C31H38ClN7O7

Molecular Weight

656.13

Precautions

H302, H315, H319

References & Citations

[1]Mosztbacher D, et al. Measuring digestive protease activation in the mouse pancreas. Pancreatology. 2020 Mar;20 (2) :288-292.|[2]Li WA, et al. Detection of femtomole quantities of mature cathepsin K with zymography. Anal Biochem. 2010 Jun 1;401 (1) :91-8.