12-Ethyl-9-hydroxycamptothecin

SN38 is the potent active metabolite of the anticancer prodrug irinotecan. As a topoisomerase I inhibitor, it is widely used in both in vitro and in vivo research models to study colorectal cancer and other malignancies.

Product Specifications

CAS Number

119577-28-5

Product Name Alternative

12 Ethyl 9 hydroxycamptothecin, 12Ethyl9hydroxycamptothecin, 12-Ethyl-9-hydroxycamptothecin, 7-Ethyl-10-Hydroxy-Camptothecin, Topo I

Field of Research

Molecular Biology

Purity

99.89% (May vary between batches)

Solubility

DMSO:80 mg/mL (203.87 mM)

Smiles

O=C1N2C (C=3C (C2) =CC=4C (N3) =C (CC) C=CC4O) =CC5=C1COC (=O) [C@@]5 (CC) O

Molecular Formula

C22H20N2O5

Molecular Weight

392.41

Storage Conditions

Keep away from direct sunlight, store at low temperature, keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.