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PBRM1-BD2-IN-8

PBRM1-BD2-IN-8 (compound 34) is a selective inhibitor of the PBRM1 bromodomain 2 (BD2), exhibiting potent binding affinity (Kd=4.4 μM) and inhibitory activity (IC50=0.16 μM) . This small molecule demonstrates anti-cancer properties in research settings, enabling the study of chromatin remodeling and gene regulation in both cellular and biochemical assays.

Product Specifications

CAS Number

2819989-75-6

Product Name Alternative

EpigeneticReaderDomain, Epigenetic Reader Domain, PBRM1BD2IN8, PBRM1-BD2-IN-8

Field of Research

Epigenetics & Chromatin

Purity

99.48% (May vary between batches)

Solubility

DMSO:55 mg/mL (173.4 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.31 mM)

Smiles

O=C1C=2C (NC (N1) C3=CC (C) =CC=C3) =CC=CC2Br

Molecular Formula

C15H13BrN2O

Molecular Weight

317.18

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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